Bruise-like cutaneous lesions as the early presentation of blastic plasmacytoid dendritic cell neoplasm

Bruise-like cutaneous lesions as the early presentation of blastic plasmacytoid dendritic cell neoplasm

Blog Article

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a very rare and highly aggressive hematopoietic malignancy associated with a poor prognosis.It has been recognized to originate from precursors of plasmacytoid dendritic cells and has recently been established as a distinct entity.The most frequent clinical presentations are prominent skin lesions, followed by alarecre.com peripheral blood, bone marrow, and other organ involvement.Treatment outcomes are often disappointing due to a high relapse rate after chemotherapy and risk of leukemic dissemination.Herein, we report a case of BPDCN in a 41-year-old man who presented with cutaneous and nasopharyngeal lesions, and achieved a complete response after systemic chemotherapy.

Dermatologists should be aware of BPDCN read more and its clinical presentations, as early diagnosis with appropriate treatment is crucial to improve its prognosis.